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2005 - present 2000 - 2004 1990 - 1999 1974 - 1989  

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85. Rauer, H., M. Pennington, M.D. Cahalan, and K.G. Chandy. 1999.
Structural conservation of the pores of calcium-activated and voltage-gated potassium channels determined by a sea anemone toxin.
Journal of Biological Chemistry 274: 21885-21892. pdf

   

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84. Wei, X., B.J. Tromberg, and M.D. Cahalan. 1999.
Mapping the sensitivity of T cells using an optical trap: polarity and minimal number of receptors for Ca2+ signaling.
Proceedings of the National Academy of Sciences U.S.A. 96: 8471-8476. pdf

   
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83. Hanson, D.C., A. Nguyen, R.J. Mather, H. Rauer, K. Koch, L.E. Burgess, J.P. Rizzi, C.B. Donovan, M.J. Bruns, P.C. Canniff, A.C. Cunningham, K.A. Verdries, E. Mena, J.C. Kath, G.A. Gutman, M.D. Cahalan, S. Grissmer, K.G. Chandy. 1999.
UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation.
British Journal of Pharmacology 126:1707-1716. pdf

 

   
 

82. Fanger, C.M., S. Ghanshani, N.J. Logsdon, H. Rauer, K. Kalman, J. Zhou, K. Beckingham, K.G. Chandy, M.D. Cahalan, and J. Aiyar. 1999.
Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCA1.
Journal of Biological Chemistry 274: 5746-5754. pdf

 

   
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81. Andersen, O.S. and M.D. Cahalan. 1999.
The 52nd annual meeting and symposium of the Society of General Physiologists. Local calcium signaling in cell physiology.
Journal of General Physiology 113:153-159. pdf

 

   
 

80. Kerschbaum, H.H. and M.D. Cahalan. 1999.
Single channel recording of a store-operated Ca2+ channel in Jurkat T lymphocytes.
Science 283: 836-839. pdf

 

   
79  

79. Kalman, K., M.W. Pennington, M.D. Lanigan, A. Nguyen, H. Rauer, V. Mahnir, K. Paschetto, W.R. Kem, S. Grissmer, G.A. Gutman, E.P. Christian, M.D. Cahalan, R.S. Norton, and K.G. Chandy. 1998.
ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
Journal of Biological Chemistry 273: 32697-32707. pdf

   

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78 Ehring, G.E., H.H. Kerschbaum, C. Eder, A.L. Neben, C.M. Fanger, R.M. Khoury, P.A. Negulescu, and M.D. Cahalan. 1998.
A nongenomic mechanism for progesterone-mediated immunosuppression: inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes.
Journal of Experimental Medicine 188: 1593-1602. pdf

   

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77. Kerschbaum, H.H. and M.D. Cahalan. 1998.
Monovalent permeability, rectification, and ionic block of store-operated calcium channels in Jurkat T lymphocytes.
Journal of General Physiology 111: 521-537. pdf

   
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76. Kalman, K., A. Nguyen, J. Tseng-Crank, I.D. Dukes, G. Chandy, C.M. Hustad, N.G. Copeland, N.A. Jenkins, H. Mohrenweiser, B. Brandriff, M. Cahalan, G.A. Gutman, and K. George Chandy. 1998.
Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.
Journal of Biological Chemistry 273: 5851-5857. pdf

 

   
 

75. Cahalan, M.D. and K.G. Chandy. 1997.
Ion channels in the immune system as targets for immunosuppression.
Current Opinion in Biotechnology 8: 749-756. pdf

 

   
   

74. Garber, S.S. and M.D. Cahalan. 1997.
Volume-regulated anion channels and the control of a simple cell behavior.
Cellular Physiology and Biochemistry 7: 229-241.

 

   
   

73. Lepple-Wienhues, A. and M.D. Cahalan. 1997.
A mysterious channel: properties of the capacitive Ca2+ channel in lymphocytes.
Cellular Physiology and Biochemistry 7: 219-228.

 

   
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72. Cahalan, M.D., and A. Lepple-Wienhues. 1997.
Ion channels in lymphocyte function: Editorial.
Cellular Physiology and Biochemistry 7: 133-134

 

   
71  

71. Ross, P.E., G.R. Ehring, and M.D. Cahalan. 1997.
Dynamics of ATP-induced calcium signaling in single mouse thymocytes.
Journal of Cell Biology 138: 987-998. pdf

 

   
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70. Kerschbaum, H.H., Negulescu, P.A. and M.D. Cahalan. 1997.
Ion channels, [Ca2+]i signaling, and gene expression in an antigen-specific reporter T cell line.
Journal of Immunology 159: 1628-1638. pdf

 

   
69  

69. Allen, D., A. Lepple-Wienhues, and M.D. Cahalan. 1997.
Ion channel phenotype of melanoma cell lines.
J. Membrane Biol. 155: 27-34. pdf

 

   
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68. Nguyen, A., J. Kath, D.C. Hanson, P.C. Kaniff, C. Donovan, R.J. Mather, M. Bruns, B. Dethlefs, H. Rauer, J. Aiyar, A. Lepple-Wienhues, G.A. Gutman, S. Grissmer, M.D. Cahalan, K.G. Chandy. 1996.
Novel non-peptide agents block the C-type inactivated conformation of Kv1.3, and suppress T-cell activation.
Molecular Pharmacology 50: 1672-1769.

 

   
 

67. Lepple-Wienhues, and M.D. Cahalan. 1996.
Conductance and permeation of monovalent ions through depletion-activated Ca2+ channels (Icrac) in Jurkat T cells.
Biophysical Journal 71: 787-794.

 

  Immunity Cover Photo
 

66. Negulescu, P.A., A. Khan, T.B. Krasieva, H.H. Kerschbaum, and M.D. Cahalan. 1996.
Polarity of T cell shape, motility, and sensitivity to antigen.
Immunity 4: 421-430. (cover illustration) pdf

 

 
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65 Ross, P.E. and M.D. Cahalan. 1995.
Ca2+ influx pathways mediated by swelling and stores depletion in mouse thymocytes.
Journal of General Physiology 106: 415-444. pdf

 

   
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64. Verheugen, J.A.H., H.P.M. Vijverberg, M. Oortgiesen, and M.D. Cahalan. 1995.
Voltage-gated and Ca2+ -activated K+ channels in intact human T lymphocytes.
Journal of General Physiology 13: 765-794. pdf

 

   
   

63. Lewis, R.S. and M.D. Cahalan. 1995.
Potassium and calcium channels in lymphocytes.
Annual Review of Immunology 13: 623-653. pdf

 

   
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62. Cahalan, M.D., Ehring G.R., and Y.V. Osipchuk. 1994.
Volume-sensitive C1- channels in lymphocytes and multidrug-resistant cell lines.
Japanese Journal of Physiology 44, S25 - S30

 

   
 

61. Ehring, G. R., Y.V. Osipchuk, and M.D Cahalan. 1994.
Swelling-activated chloride channels in multidrug-sensitive and -resistant cells.
Journal of General Physiology 104: 1129-1161. pdf

 

   
 

60. Cahalan, M.D. and R.S. Lewis. 1994.
Regulation of chloride channels in lymphocytes.
pp. 103-129 in Current Topics in Membranes Vol. 42. Chloride Channels. William Guggino (ed.), Academic Press, San Diego.

 

   
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59. Negulescu, P., N. Shastri, and M.D. Cahalan. 1994.
Intracellular calcium dependence of IL-2 gene expression in single T lymphocytes.
Proceedings of the National Academy of Sciences U.S.A. 91: 2873-2877. pdf

 

   
 

58. Grissmer, S., A.N. Nguyen, and M.D. Cahalan. 1993
Calcium-activated potassium channels in resting and activated human T lymphocytes.
Journal of General Physiology 102: 601-630.pdf

 

   
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57. Ross, P., S. Garber, and M.D. Cahalan. 1993.
Membrane chloride conductance and capacitance in Jurkat T lymphocytes during osmotic swelling.
Biophysical Journal 66: 169-178.

 

   
 

56. Lewis, S., P. Ross, and M.D. Cahalan. 1993.
Chloride channels activated by osmotic stress in T lymphocytes.
Journal of General Physiology 101: 801-826. pdf

 

   
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55. Hess, S., M. Oortgiesen, and M.D. Cahalan. 1993
Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx.
Journal of Immunology 150: 2620-2633. pdf

 

   
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54. Grissmer, S., S. Ghanshani, B. Dethlefs, J. McPherson, J. Wasmuth, G. Gutman, M.D. Cahalan, and K.G. Chandy. 1992
.The Shaw-related potassium-channel gene, Kv3.1, on human chromosome 11, encodes the type l K+ channel in T Cells.
Journal of Biological Chemistry 267: 20971-20979. pdf

 

   
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53. Osipchuk, Y. and M.D. Cahalan. 1992.
Cell-to-cell spread of calcium signals mediated by ATP receptors in a mast cell line.
Nature 359: 241-244.

 

   
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52. Grissmer, S., R.S. Lewis, and M.D. Cahalan. 1992.
Ca2+-activated K+ channels in human leukemic T cells.
Journal of General Physiology 99: 1-23. pdf

 

   
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51. Cahalan, M.D. and E. Neher. 1992.
Patch clamp techniques: an overview.
pp.1-14 in Methods in Enzymology, Vol. 207, Modern Applications of Electrophysiological Techniques. B. Rudy and L. Iverson (eds.) Academic Press, San Diego.

 

   
 

50. Cahalan, M.D., K.G. Chandy, and S. Grissmer. 1992.
Potassium channels in development, activation, and disease in T lymphocytes.
pp. 357-394 in Current Topics in Membranes, Vol. 39, Developmental Biology of Membrane Transport Systems. D.J. Benos (ed.) Academic Press, San Diego.

 

   
   

49. Grissmer, S., D. Hanson, P. Natale, M.D. Cahalan, and K.G. Chandy. 1990.
CD4- CD8- T cells from mice with collagen arthritis display aberrant expression of type l K+ channels.
Journal of Immunology 145: 2105-2109. pdf

 

   
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48. Grissmer, S., B. Dethlefs, J. Wasmuth, A.L. Goldin, G.A. Gutman, M.D. Cahalan, and K.G. Chandy. 1990.
Expression and chromosomal localization of a lymphocyte K+ channel gene.
Proceedings of the National Academy of Sciences U.S.A. 87: 9411-9415. pdf

 

   
 

47. Cahalan, M.D. and R.S. Lewis. 1990.
Functional roles of ion channels in lymphocytes.
Seminars in Immunology 2: 107-117.

 

   
   

46. Lewis, R.S. and M.D. Cahalan. 1990.
Ion channels and signal transduction in lymphocytes.
Annual Review of Physiology 52: 415-430. pdf

 

   
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45. McCloskey, M.A. and M.D. Cahalan. 1990.
G-protein control of potassium channel activity in a mast cell line.
Journal of General Physiology 95: 205-227. pdf

 

   
 

44. Lewis, R.S. and M.D. Cahalan. 1990.
Ion channels and calcium signaling in single mitogen-stimulated T lymphocytes.
UCLA Symposia on Molecular and Cellular Biology 113: 125-132.

 

   
   

43. Chandy, K.G., M.D. Cahalan, and S. Grissmer. 1990.
Autoimmune diseases linked to abnormal K+ channel expression in double-negative CD4- CD8- T cells
European Journal of Immunology 20: 747-751.

 

   
 
 

Maintained by
Jeff Ingeman
Physiology and Biophysics, University of California,Irvine, CA, USA, 92697-4561
Phone: (949) 824-6754 • Fax: (949) 824-3143 • Email:mcahalan@uci.edu

Last updated
04/17/2006