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2005 - present 2000 - 2004 1990 - 1999 1974 - 1989  

 

120. Miller, M.J., A. Safrina, I. Parker, and M.D. Cahalan. 2004.
Imaging the single-cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes.
Journal of Experimental Medicine 200: 847-856. pdf

 

   
 

119. Chandy, K.G., H. Wulff, C. Beeton, M. Pennington, G.A. Gutman, M.D. Cahalan. 2004.
Potassium channels as targets for specific immunosuppression.
Trends in Pharmacological Sciences 25: 280-289. pdf

 

   
 

118. Yeromin A.V., J. Roos, K.A. Stauderman, and M.D. Cahalan. 2004.
A store-operated calcium channel in Drosophila S2 cells.
Journal of General Physiology 123: 167-182. pdf

 

  Faculty of 1000 Biology

 

117. Miller, M.J., A.S. Hejazi, S.H. Wei, I. Parker, and M.D. Cahalan. 2004.
T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node.
Proceedings of the National Academy of Sciences U.S.A. 101: 998-1003. pdf

  Faculty of 1000 Biology
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116. Kolski-Andreaco, A.A., H. Tomita, V.G. Shakkottai, G.A. Gutman, M.D. Cahalan, J.J. Gargus, and K.G. Chandy. 2004.
SK3-1C: a dominant-negative suppressor of SKCa and IKCa channels.
Journal of Biological Chemistry 279: 6893-6904. pdf

   
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115. Wei, S., I. Parker, M.J. Miller, and M.D. Cahalan. 2003.
A stochastic view of lymphocyte motility and trafficking within the lymph node.
Immunological Reviews 195: 136-159. (cover illustration) pdf

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114. Cahalan, M.D., I. Parker, S.H. Wei, and M.J. Miller. 2003.
Real time imaging of lymphocytes in vivo.
Current Opinion 15: 372-377. pdf

 
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113. Fomina, A.F, T.J. Deerinck, M.H. Ellisman, and M.D. Cahalan. 2003.
Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells.
Experimental Cell Research 291 150-166. pdf

   

112
 

112. Tomita, H., Tomita, V.G. Shakkottai, G.A. Gutman, G. Sun, W.E. Bunney, M.D. Cahalan, K.G. Chandy, and J.J. Gargus. 2003.
Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia.
Molecular Psychiatry 8: 524-535. pdf, fig

   

111
 

111. Beeton, C, H. Wulff, S. Singh, S. Botsko, G. Crossley, G.A. Gutman, M.D. Cahalan, M. Pennington, and K.G. Chandy. 2003.
A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes.
Journal of Biological Chemistry 278: 9928-9937. pdf

   
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110. Miller, M.M., S.H. Wei, I. Parker, and M.D. Cahalan. 2003.
Autonomous T cell trafficking examined in vivo using intravital two-photon microscopy.
Proceedings of the National Academy of Sciences U.S.A. 100: 2604-2609. pdf

  Faculty of 1000 Biology
109  

109. Kerschbaum, H.H., J.A. Kozak, and M.D. Cahalan. 2003.
Polyvalent cations as permeant probes of MIC and TRPM7 pores.
Biophysical Journal 84:2293-305. pdf

 

   
108  

108. Kozak, J.A. and M.D. Cahalan. 2003.
MIC channels are inhibited by internal divalent cations but not ATP.
Biophysical Journal 84: 922-927. pdf

 

   
107  

107. Cahalan, M.D., I. Parker, S.H. Wei, and M.J. Miller. 2002
.Two photon tissue imaging: seeing the immune response in a fresh light.
Nature Reviews Immunology 2: 872-880. pdf

 

   
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106. Wei, S.H., M.J. Miller, M.D. Cahalan, and I. Parker. 2002.
Two-photon imaging in intact lymphoid tissue.
Adv. Exp. Med. Biol. 512:203-208. pdf

 

   
 

105. Kozak, J.A., H.H. Kerschbaum, and M.D. Cahalan. 2002.
Distinct properties of CRAC and MIC channels in RBL cells.
Journal of General Physiology 120: 8601-8615. pdf

 

   
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104. Miller, M.M., S.H. Wei, I. Parker, and M.D. Cahalan. 2002.
Two-photon imaging of lymphocyte motility and dynamic antigen responses in intact lymph node.
Science 296: 1869-1873. pdf

 

  Faculty of 1000 Biology
 

103. Cahalan, M.D. 2002.
Ins and outs of polycystin-2 as a Ca2+-release channel.
Nature Cell Biology 4: E56-E57. pdf

 

   
101  

102. Ayabe, T. H.Wulff, D. Darmoul, M.D. Cahalan, K.G. Chandy, A.J. Ouellette. 2002.
Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated intermediate-conductance potassium channel.
Journal of Biological Chemistry 277: 3793-3800. pdf

 

   
 

101. Shakkottai, V.G., I Regaya, H. Wulff, Z. Failoun, H. Tomita, M. Fathallah, M.D. Cahalan, J.J. Gargus, J.M. Sabatier, and K.G. Chandy. 2001.
Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SKCa2.
Journal of Biological Chemistry 276:43145-43151. pdf

 

   

100
 

100. Beeton, C., H. Wulff, J. Barbaria, O. Clot-Faybesse, M. Pennington, D. Bernard, M.D. Cahalan, K.G. Chandy, and E. Beraud. 2001.
Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalitis, a model for multiple sclerosis.
Proceedings of the National Academy of Sciences U.S.A. 98: 13942-13947. pdf

   

99
 

99. Wulff, H., G.A. Gutman, M.D. Cahalan, and K.G. Chandy. 2001.
Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1.
Journal of Biological Chemistry 276: 32040-32045. pdf

   

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98. Miller, M.J., H. Rauer, H. Tomita, H. Rauer, J.J. Gargus, G.A. Gutman, M.D. Cahalan, and K.G. Chandy. 2001.
Nuclear localization and dominant negative suppression by a mutant SKCa3 N-terminal channel fragment identified in a patient with schizophrenia.
Journal of Biological Chemistry 276: 27753-27756. pdf

   
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97. Cahalan, M.D. 2001.
Channels as enzymes.
Nature 411: 542-543. pdf

 

   
 

96. Cahalan, M.D., H. Wulff, and K.G. Chandy. 2001.
Molecular properties and physiological roles of ion channels in T lymphocytes.
Journal of Clinical Immunology 21:235-252. pdf

 

   
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95. Chandy, K.G., M.D. Cahalan, M. Pennington, R.S. Norton, H. Wulff, and G.A. Gutman. 2001.
Potassium channels in T lymphocytes: toxins to therapeutic immunosuppressants.
Toxicon 39: 1269-1276. pdf

 

   

94
 

94. Fanger, C., H. Rauer, A.L. Neben, M.J. Miller, H. Rauer, H. Wulff, J.C. Rosa, C.R. Ganellin, K.G. Chandy, and M.D. Cahalan. 2001.
Calcium-activated potassium channels sustain calcium signaling in T lymphocytes; Selective blockers and manipulated expression levels.
Journal of Biological Chemistry 276: 12249-12256. pdf

 

   
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93. Ghanshani, S., H. Wulff, M.J. Miller, H. Rohm, A.L. Neben, G.A. Gutman, M.D. Cahalan, and K.G. Chandy. 2000.
Up-regulation of the IKCa1 potassium channel during T-cell activation: molecular mechanism and functional consequences.
Journal of Biological Chemistry 275: 37137-37149. pdf

 

   
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92. Fomina, A.F., C.M. Fanger, J.A. Kozak, and M.D. Cahalan. 2000.
Single-channel properties and regulated expression of Ca2+ release-activated Ca2+ channels in resting and activated human T lymphocytes.
Journal of Cell Biology 150: 1435-1444. pdf

 

   
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91. Wulff, H., M.D. Cahalan, and K.G. Chandy. 2000.
Design of a potent and selective inhibitor of the intermediate conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant.
Proceedings of the National Academy of Sciences U.S.A. 97: 8151-8156. pdf

 

   
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90. Leissring, M.A., Y. Akbari, C.M. Fanger, M.D. Cahalan, M.P. Mattson, and F.M. LaFerla. 2000.
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knock-in mice.
Journal of Cell Biology 149: 793-797. pdf

 

   
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89. Wei, X., M-S. Si, D.K. Imagawa, P. Ji, B.J. Tromberg, and M.D. Cahalan. 2000.
Perillyl alcohol inhibits TCR-mediated [Ca2+]i signaling, alters cell shape and motility, and induces apoptosis in T lymphocytes.
Cellular Immunology 201: 6-13. pdf

 

   
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88. Fanger, C.M., A. Neben, and M.D. Cahalan. 2000.
Differential Ca2+ influx, KCa channel activity and Ca2+ clearance distinguish Th1 and Th2 lymphocytes.
Journal of Immunology 164: 1153-1160. pdf

 

   
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87. Rauer, H., M.D. Lanigan, M.W. Pennington, J. Aiyar, S. Ghanshani, M.D. Cahalan, R.S. Norton, and K.G. Chandy. 2000.
Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca2+-activated over voltage-gated K+ channels.
Journal of Biological Chemistry 275: 1201-1208. pdf

 

 
86   86. Ehring, G.E., H.H. Kerschbaum, C. Eder, C.M. Fanger, H. Rauer, and M.D. Cahalan. 2000.
Vanadate induces calcium signaling in T lymphocytes and RBL-2H3 mast cells via thiol oxidation.
Journal of Immunology 164: 679-687. pdf
 
 
 

Maintained by
Jeff Ingeman
Physiology and Biophysics, University of California,Irvine, CA, USA, 92697-4561
Phone: (949) 824-6754 • Fax: (949) 824-3143 • Email:mcahalan@uci.edu

Last updated
04/17/2006